Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1993 Jun;32(2):131-8.
doi: 10.1007/BF01614756.

[The combination effects of quercetin with the herbicides atrazine, cyanazine and gesamprim in mutagenicity tests]

[Article in German]
C Guigas  1 , B L Pool-Zobel, J F Diehl
Affiliations

[The combination effects of quercetin with the herbicides atrazine, cyanazine and gesamprim in mutagenicity tests]

[Article in German]
C Guigas et al. Z Ernahrungswiss. 1993 Jun.

Abstract

The plant flavonol quercetin and the triazine herbicides atrazine, cyanazine, and gesamprim were examined individually and in combination for the induction of genotoxic effects. The sister chromatid exchange (SCE) assay and the gene mutation assay for 6-thioguanine resistance (HPRT) were carried out with Chinese hamster ovary (CHO) cells. Whereas no evidence of an increased SCE rate was found, the test substances caused a slightly increased mutation rate in the HPRT assay after metabolic activation with a subcellular liver enzyme preparation. Combination studies with two or three of the test substances did not result in higher mutation rates than those observed for the individual compounds tested singly.

PubMed Disclaimer

References

    1. Science. 1977 Aug 5;197(4303):577-8 - PubMed
    1. Mutat Res. 1988 Oct;206(2):221-5 - PubMed
    1. Mutat Res. 1980 May;75(3):243-77 - PubMed
    1. Jpn J Cancer Res. 1989 Aug;80(8):732-6 - PubMed
    1. Mutat Res. 1990 Oct;232(2):243-8 - PubMed

Publication types

LinkOut - more resources