Toxicological investigations of cases of death involving codeine and dihydrocodeine
- PMID: 838412
- DOI: 10.1016/0300-9432(77)90061-9
Toxicological investigations of cases of death involving codeine and dihydrocodeine
Abstract
Drug levels in post-mortem specimens from 6 cases of poisoning involving codeine or dihydrocodeine have been determined using a direct extraction method followed by gas liquid chromatography. The relevant case histories are described. A preliminary qualitative investigation of dihydrocodeine metabolism has been described involving the analysis of urine samples by thin layer and gas chromatography.
Similar articles
-
The role of dihydrocodeine (DHC) metabolites in dihydrocodeine-related deaths.J Anal Toxicol. 2010 Oct;34(8):476-90. doi: 10.1093/jat/34.8.476. J Anal Toxicol. 2010. PMID: 21819793
-
The detection of dihydrocodeine and its main metabolites in cases of fatal overdose.Int J Legal Med. 1999;112(3):155-8. doi: 10.1007/s004140050222. Int J Legal Med. 1999. PMID: 10335876
-
Gas chromatography with surface ionization detection: a highly sensitive method for determining underivatized codeine and dihydrocodeine in body fluids.J Chromatogr B Biomed Appl. 1995 Nov 17;673(2):189-95. doi: 10.1016/0378-4347(95)00275-1. J Chromatogr B Biomed Appl. 1995. PMID: 8611952
-
Chromatographic separation of 2,3-benzodiazepines.J Chromatogr B Biomed Sci Appl. 2000 Sep 29;747(1-2):203-16. doi: 10.1016/s0378-4347(00)00269-3. J Chromatogr B Biomed Sci Appl. 2000. PMID: 11103906 Review.
-
Guide to urine testing in drug abuse prevention and multi-modality treatment programs.J Chromatogr. 1977 Aug 21;141(2):145-96. doi: 10.1016/s0021-9673(00)99132-5. J Chromatogr. 1977. PMID: 19493 Review. No abstract available.
Cited by
-
Codeine concentrations in human samples in a case of fatal ingestion.Int J Legal Med. 1991;104(3):177-8. doi: 10.1007/BF01369725. Int J Legal Med. 1991. PMID: 1911418
-
Drug dependence caused by dihydrocodeine.Br Med J. 1978 Jun 17;1(6127):1594. doi: 10.1136/bmj.1.6127.1594. Br Med J. 1978. PMID: 656829 Free PMC article. No abstract available.
-
Opiate toxicity after self poisoning with aspirin and codeine.Br Med J (Clin Res Ed). 1986 Jan 11;292(6513):96. doi: 10.1136/bmj.292.6513.96. Br Med J (Clin Res Ed). 1986. PMID: 3002537 Free PMC article. No abstract available.
-
Dihydrocodeine narcosis in renal failure.Br Med J (Clin Res Ed). 1983 Feb 5;286(6363):438-9. doi: 10.1136/bmj.286.6363.438-a. Br Med J (Clin Res Ed). 1983. PMID: 6401554 Free PMC article. No abstract available.