Heterogeneity of Wilson's disease in Israel
- PMID: 838566
Item in Clipboard
Heterogeneity of Wilson's disease in Israel
Isr J Med Sci.
1977 Jan.
Abstract
In a survey in Israel of 50 patients with Wilson's disease, it was found that this disease occurred in all ethnic groups. In the Arab patients there was a significantly early age of onset and the disease followed a more severe course than that in the Jewish patients. The overall sex ratio of patients was nearly 1:1, and genetic analysis of 20 families confirmed an autosomal recessive mode of inheritance. The very similar age of onset and type of disease within sibships and the varying ages of onset noted between the Arab and Jewish patients suggest that the disease is genetically heterogeneous.
Similar articles
-
[Wilson's disease in the German Democratic Republic. I. Genetics and epidemiology].Z Gesamte Inn Med. 1979 Dec 15;34(24):744-8. Z Gesamte Inn Med. 1979. PMID: 549306 German.
-
Wilson's disease--a review of cases at University Hospital, Kuala Lumpur.Med J Malaysia. 1994 Mar;49(1):49-52. Med J Malaysia. 1994. PMID: 8057991
-
[Epidemiologic study of Wilson's disease in West Germany].Nervenarzt. 1987 Mar;58(3):150-7. Nervenarzt. 1987. PMID: 3495740 German. No abstract available.
-
Wilson's disease in Turkey, a review of 49 cases in 41 families.New Istanbul Contrib Clin Sci. 1975 Jun;11(2):92-7. New Istanbul Contrib Clin Sci. 1975. PMID: 1107956 Review. No abstract available.
-
[Wilson's disease in East Germany: in retrospect and perspectives -- an evaluation].Psychiatr Neurol Med Psychol (Leipz). 1990 Oct;42(10):585-600. Psychiatr Neurol Med Psychol (Leipz). 1990. PMID: 2077550 Review. German.
Cited by
-
Assignment of the gene for Wilson disease to chromosome 13: linkage to the esterase D locus.Proc Natl Acad Sci U S A. 1985 Mar;82(6):1819-21. doi: 10.1073/pnas.82.6.1819. Proc Natl Acad Sci U S A. 1985. PMID: 3856863 Free PMC article.
-
Mapping the Wilson disease locus to a cluster of linked polymorphic markers on chromosome 13.Am J Hum Genet. 1987 Jul;41(1):27-35. Am J Hum Genet. 1987. PMID: 3474893 Free PMC article.
-
Secondary athrocytotic cardiomyopathy--heart damage due to Wilson's disease.Virchows Arch A Pathol Anat Histol. 1980;387(1):67-80. doi: 10.1007/BF00428430. Virchows Arch A Pathol Anat Histol. 1980. PMID: 7467117
-
Predicting genotypes at loci for autosomal recessive disorders using linked genetic markers: application to Wilson's disease.Hum Genet. 1988 Jun;79(2):109-17. doi: 10.1007/BF00280547. Hum Genet. 1988. PMID: 3164701
-
Linkage of the Wilson disease gene to chromosome 13 in North-American pedigrees.Am J Hum Genet. 1988 Jun;42(6):825-9. Am J Hum Genet. 1988. PMID: 3163469 Free PMC article.