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Review
. 1993;18(2):63-70.
doi: 10.3109/10715769309147343.

Oxygen radicals, a failure or a success of evolution?

G Barja  1
Affiliations
Review

Oxygen radicals, a failure or a success of evolution?

G Barja. Free Radic Res Commun. 1993.

Abstract

Oxygen radicals are no doubt involved in the development of many pathological states. Nevertheless, the possibility that oxygen radical production was selected for during biological evolution in order to perform useful roles in relation to cellular metabolism is contemplated; previous data on this subject are briefly reviewed. The concept of an "oxygen radical cycle" is proposed as a useful theoretical model.

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