Review
doi: 10.1002/ajmg.1320460103.
Cytogenetic and molecular studies in the Prader-Willi and Angelman syndromes: an overview
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- PMID: 8388170
- DOI: 10.1002/ajmg.1320460103
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Review
Cytogenetic and molecular studies in the Prader-Willi and Angelman syndromes: an overview
Am J Med Genet.
.
Abstract
The majority of patients with Angelman syndrome and Prader-Willi syndrome have a cytogenetic and molecular deletion of chromosome 15q11q13 with the primary difference being in the parental origin of deletion. Our current understanding of the cytogenetics and molecular genetics of these 2 clinically distinct syndromes will be discussed in this review.
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