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Comparative Study
. 1993 Jul;67(7):4391-4.
doi: 10.1128/JVI.67.7.4391-4394.1993.

An African swine fever virus gene with similarity to the proto-oncogene bcl-2 and the Epstein-Barr virus gene BHRF1

J G Neilan  1 , Z Lu, C L Afonso, G F Kutish, M D Sussman, D L Rock
Affiliations
Comparative Study

An African swine fever virus gene with similarity to the proto-oncogene bcl-2 and the Epstein-Barr virus gene BHRF1

J G Neilan et al. J Virol. 1993 Jul.

Abstract

An open reading frame, LMW5-HL, in the African swine fever virus genome displays a high degree of similarity to the proto-oncogene bcl-2 and, to a lesser degree, the Epstein-Barr virus gene BHRF1. A highly conserved central region is found in all three proteins. LMW5-HL encodes a protein of 18 kDa that is present in infected porcine macrophages at both early and late times postinfection. The similarity of LMW5-HL to bcl-2 and BHRF1 suggests a role for it in cell maintenance during productive or persistent viral infection.

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References

    1. Cornell Vet. 1968 Jul;58(3):364-88 - PubMed
    1. J Mol Biol. 1989 Dec 20;210(4):749-69 - PubMed
    1. Vet Rec. 1969 Dec 13;85(24):668-74 - PubMed
    1. Cornell Vet. 1971 Jan;61(1):125-50 - PubMed
    1. Cornell Vet. 1971 Jan;61(1):71-84 - PubMed

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