Review
doi: 10.1080/17843286.1993.11718292.
Immunointervention in type 1 (insulin-dependent) diabetes mellitus
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- PMID: 8392249
- DOI: 10.1080/17843286.1993.11718292
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Review
Immunointervention in type 1 (insulin-dependent) diabetes mellitus
Acta Clin Belg.
1993.
Abstract
The hitherto identified hallmarks of the autoimmune aspects in Type 1 diabetes are reviewed. Their implication in the disclosure of the pre-clinical phase of the disease is put forward. The possible delineation of this pre-diabetic phase can lead to an early immunotherapeutic approach. The effect of immunomodulation by agents such as azathioprine, cyclosporin A and nicotinamide in newly diagnosed diabetes and the use of some of these drugs in clinical trials on pre-diabetic individuals are discussed.
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