Divergent differentiation in small round-cell tumours of the soft tissues with neural features--an analysis of 10 cases
- PMID: 8396064
- DOI: 10.1111/j.1365-2559.1993.tb01177.x
Divergent differentiation in small round-cell tumours of the soft tissues with neural features--an analysis of 10 cases
Abstract
A series of 10 small round-cell tumours, having in common evidence of neural differentiation, were investigated by immunohistochemistry and electronmicroscopy. In seven, evidence of divergent muscle and/or epithelial differentiation was found. This phenomenon thus appears more common than previously appreciated and suggests that there may be a continuous and overlapping phenotypic spectrum from Ewing's tumour of soft tissue to intra-abdominal desmoplastic small cell tumour.
Comment in
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Divergent differentiation in round-cell tumours of soft tissues: an interim appraisal.Histopathology. 1993 Jul;23(1):93-7. doi: 10.1111/j.1365-2559.1993.tb01191.x. Histopathology. 1993. PMID: 8396065 Review. No abstract available.
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