Construction of the full local similarity map for two biopolymers
- PMID: 8397009
- DOI: 10.1016/0303-2647(93)90062-h
Construction of the full local similarity map for two biopolymers
Abstract
A novel algorithm for construction of complete maps of local similarity for two biopolymer sequences is described. The algorithm is much faster than the related Altschul-Erickson procedure, it is implemented as the Dot-Helix module within the GeneBee package. Performance of the algorithm is exemplified with the analysis of the polyproteins of two poliovirus type 3 strains and its effectivity is compared to the Staden method. Possible applications of the algorithm are briefly discussed.
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