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Review
. 1993 Jul-Aug;33(4):529-36.

[Multigeneration carcinogenesis in the evaluation and prognosis of delayed radiation effects]

[Article in Russian]
V N Malakhovskiĭ, P V Antonov
  • PMID: 8401874
Review

[Multigeneration carcinogenesis in the evaluation and prognosis of delayed radiation effects]

[Article in Russian]
V N Malakhovskiĭ et al. Radiats Biol Radioecol. 1993 Jul-Aug.

Abstract

Radiation multigeneration carcinogenesis' mechanisms are associated with inheritance of non-specific genome lesions. Evidence indicates that the effect is significantly enhanced by some chemical carcinogens action on the offspring of irradiated parents. Hereditary character of the phenomenon is a prerequisite to accumulation of these genetic determinants in the population. The risk of radiation multigeneration carcinogenesis for man could be as much as 0.4 x 10(-2) Sv-1 over one generation.

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