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Case Reports
. 1993 Sep;40(9):863-5.
doi: 10.1007/BF03009258.

Delayed seizures following sedation with propofol

G A Finley  1 , B MacManus, S E Sampson, C V Fernandez, R Retallick
Affiliations
Case Reports

Delayed seizures following sedation with propofol

G A Finley et al. Can J Anaesth. 1993 Sep.

Abstract

Seizures occurred in two adolescents approximately six hours after sedation with propofol for bone marrow biopsy. Case #1 was a patient with chronic renal failure, hypertension, and anaemia. Case #2 had just been diagnosed with acute lymphocytic leukaemia. Neither child had experienced seizures before, and both recovered without neurological sequelae. Although other factors may have caused the seizures, the episodes have raised concerns about the safety of propofol for patients travelling home after out-patient surgery. Further study is required to explain the cause of this complication or, at least, to identify risk factors.

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Comment in

  • Propofol-related convulsions.
    Bevan JC. Bevan JC. Can J Anaesth. 1993 Sep;40(9):805-9. doi: 10.1007/BF03009247. Can J Anaesth. 1993. PMID: 8403171 English, French. No abstract available.

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