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. 1993 Jul;18(4):309-13.
doi: 10.1111/j.1365-2230.1993.tb02204.x.

Immunohistopathological spectrum in cutaneous tuberculosis

V N Sehgal  1 , R Gupta, M Bose, K Saha
Affiliations

Immunohistopathological spectrum in cutaneous tuberculosis

V N Sehgal et al. Clin Exp Dermatol. 1993 Jul.

Abstract

Granulomas of lupus vulgaris were characterized by a raised CD4+/CD8+ ratio, while in scrofuloderma this was significantly decreased. Tuberculosis verrucosa cutis showed intermediate changes. These immunological variations suggest that cutaneous tuberculosis forms a spectrum with strong cell-mediated immunity seen in lupus vulgaris, and weaker cell-mediated responses in scrofuloderma; tuberculosis verrucosa cutis is intermediate between the two.

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