Cloning and characterization of human TNF alpha promoter region
- PMID: 8406029
- DOI: 10.1016/0378-1119(93)90314-s
Cloning and characterization of human TNF alpha promoter region
Abstract
We report the sequence of a 1.2-kb human tumor necrosis factor alpha (TNF alpha) promoter region, which was cloned using PCR. The sequence has several variations from two previous reports and exhibits many potential DNA-binding sites specific to mammalian gene regulatory proteins inducible by lipopolysaccharides.
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