Review
doi: 10.1111/j.1399-3011.1993.tb00486.x.
Multistep deprotection for peptide chemistry
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- PMID: 8407114
- DOI: 10.1111/j.1399-3011.1993.tb00486.x
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Review
Multistep deprotection for peptide chemistry
Int J Pept Protein Res.
1993 Aug.
Abstract
This review article focuses on some concepts which make use of special classes of protecting groups (protected protecting groups) in peptide synthesis. Terms such as gradative deprotection, dual deprotection, two-step deprotection, safety-catch protection and multidetachable protecting systems are discussed, and the general mechanistic considerations for the deprotection process are described.
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