doi: 10.1016/0090-6980(77)90038-7.
Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma
- PMID: 841103
- DOI: 10.1016/0090-6980(77)90038-7
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Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma
Prostaglandins.
1977 Jan.
Abstract
A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).
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