Case Reports
doi: 10.1016/s0140-6736(79)90522-1.
Haematin therapy and leucocyte delta-aminolevulinic-acid-synthase activity in prolonged attack of acute porphyria
- PMID: 84154
- DOI: 10.1016/s0140-6736(79)90522-1
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Case Reports
Haematin therapy and leucocyte delta-aminolevulinic-acid-synthase activity in prolonged attack of acute porphyria
Lancet.
.
Abstract
The activity of leucocyte delta-aminolaevulinic-acid (A.L.A.) synthase was monitored throughout a prolonged attack of acute intermittent porphyria in a 29-year-old women. Clinical severity was associated with a pronounced increase in activity of this enzyme and high urinary excretion of A.L.A. Haematin therapy resulted in clinical improvement associated with a reduction in the activity of A.L.A. synthase and reduction in urinary excretion of A.L.A.
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