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Comparative Study
. 1993 Jan;67(1):548-52.
doi: 10.1128/JVI.67.1.548-552.1993.

Borna disease virus in mice: host-specific differences in disease expression

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Comparative Study

Borna disease virus in mice: host-specific differences in disease expression

S A Rubin et al. J Virol. 1993 Jan.

Abstract

We developed a mouse model of Borna disease to facilitate immunopathogenesis research by adaptation of Borna disease virus to mice through serial passage in mouse brain tissue. Borna disease virus replication, antibody production, inflammation, and Borna disease expression in several different strains of mice were examined.

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