Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1993 Feb;61(2):768-71.
doi: 10.1128/iai.61.2.768-771.1993.

The gamma-hemolysin locus of Staphylococcus aureus comprises three linked genes, two of which are identical to the genes for the F and S components of leukocidin

J Cooney  1 , Z Kienle, T J Foster, P W O'Toole
Affiliations

The gamma-hemolysin locus of Staphylococcus aureus comprises three linked genes, two of which are identical to the genes for the F and S components of leukocidin

J Cooney et al. Infect Immun. 1993 Feb.

Abstract

The Staphylococcus aureus gamma-hemolysin comprises two polypeptides, whereas the gamma-hemolysin locus (hlg) contains three open reading frames. The hlgA and hlgB genes encode the gamma 1 and gamma 2 components, respectively. The HlgB protein (gamma 2) has 27% residue identity with S. aureus alpha-toxin. Surprisingly, hlgB and hlgC are 98.5 and 99.1% identical to the lukF and lukS genes, respectively, encoding the F and S components of the Panton-Valentine leukocidin.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Biochem Biophys Res Commun. 1992 Apr 30;184(2):640-6 - PubMed
    1. J Gen Microbiol. 1992 May;138(5):923-30 - PubMed
    1. Biochem J. 1960 Apr;75:158-65 - PubMed
    1. Ann Inst Pasteur (Paris). 1970 Jan;118(1):19-33 - PubMed
    1. Infect Immun. 1974 Jul;10(1):54-9 - PubMed

Publication types

Associated data

LinkOut - more resources