The inherent DNase of pyocin AP41 causes breakdown of chromosomal DNA
- PMID: 8423163
- PMCID: PMC196246
- DOI: 10.1128/jb.175.3.912-915.1993
The inherent DNase of pyocin AP41 causes breakdown of chromosomal DNA
Abstract
Pyocin AP41 degrades the chromosomal DNA in sensitive strains of Pseudomonas aeruginosa but has little effect on RNA, protein, and lipid syntheses. In vitro experiments showed that the carboxyl-terminal part of the large subunit of pyocin AP41 carries an inherent DNase that is responsible for its killing action.
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