Increase of Parkinson disability after fluoxetine medication
- PMID: 8423889
- DOI: 10.1212/wnl.43.1_part_1.211
Increase of Parkinson disability after fluoxetine medication
Abstract
Depression is a major clinical feature of Parkinson's disease. We report the increased amount of motor disability in four patients with idiopathic Parkinson's disease after exposure to the antidepressant fluoxetine. The possibility of a clinically relevant dopamine-antagonistic capacity of fluoxetine in Parkinson's disease patients must be considered.
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