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. 1977 Mar;34(3):142-4.
doi: 10.1001/archneur.1977.00500150028004.

Brain-type creatine kinase isoenzyme. Occurrence in serum in acute cerebral disorders

M Kaste, H Somer, A Konttinen

Brain-type creatine kinase isoenzyme. Occurrence in serum in acute cerebral disorders

M Kaste et al. Arch Neurol. 1977 Mar.

Abstract

Acute brain damage-cerebrovascular or cardiovascular, traumatic or infectious-released brain-type isoenzyme of creatine kinase (BB-CK) into the circulation within a few hours in 16 of 62 patients (26%). Occurrence of BB-CK was transient in the serum. BB-CK activity was found in the peripheral blood in 13 of 23 patients with diffuse brain damage compared to three of 39 patients with a local cerebrovascular accident (P less than .0005). The mortality of patients having BB-CK in their serum was 63% compared to 39% of those without BB-CK activity in their serum (P less than .05).

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