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. 1993 Feb;43(2):414-7.
doi: 10.1212/wnl.43.2.414.

Frequent presence of anti-GQ1b antibody in Fisher's syndrome

N Yuki  1 , S Sato, S Tsuji, T Ohsawa, T Miyatake
Affiliations

Frequent presence of anti-GQ1b antibody in Fisher's syndrome

N Yuki et al. Neurology. 1993 Feb.

Abstract

We used the enzyme-linked immunosorbent assay to investigate autoantibodies against the gangliosides GM1, GD1a, GD1b, GT1b, GD2, and GQ1b in sera from 16 patients with Fisher's syndrome. We found high anti-GQ1b antibody titers, mainly those of the IgG class, in the sera of 13 of these patients. The titers decreased with the clinical course of the illness. Moreover, anti-GQ1b antibody-positive patients had more severe ataxia of cerebellar type than the antibody-negative patients.

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Comment in

  • Fisher's syndrome.
    Sternman D, Braun C. Sternman D, et al. Neurology. 1994 Feb;44(2):360. doi: 10.1212/wnl.44.2.360. Neurology. 1994. PMID: 8309593 No abstract available.

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