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. 1993 Feb 20;1172(1-2):181-3.
doi: 10.1016/0167-4781(93)90289-p.

Cloning and structural analysis of genomic DNA for human renal dipeptidase

S Satoh  1 , C Kusunoki, Y Konta, M Niwa, M Kohsaka
Affiliations

Cloning and structural analysis of genomic DNA for human renal dipeptidase

S Satoh et al. Biochim Biophys Acta. .

Abstract

A genomic DNA for human renal dipeptidase was isolated from a human genomic library using probes for human renal dipeptidase cDNA. The human renal dipeptidase gene, containing ten exons and nine introns, had a total length of approx. 6 kbp. The DNA sequence of these exons was slightly different from that of the human renal dipeptidase cDNA reported by Adachi et al. [1]. From the results of a comparison of the deduced amino acid sequence of each exon with various mammalian renal dipeptidases, the fourth exon was found to be highly conserved (90%).

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