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. 1993 Mar 8;318(3):231-4.
doi: 10.1016/0014-5793(93)80518-y.

Presence of lipocortins I and IV, but not II and VI, in human platelets

J A Eldering  1 , M Kocher, J M Clemetson, K J Clemetson, F J Frey, B M Frey
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Free article

Presence of lipocortins I and IV, but not II and VI, in human platelets

J A Eldering et al. FEBS Lett. .
Free article

Abstract

The present investigation revealed the presence of lipocortins I and IV, but not lipocortins II and VI, in human platelets. Lipocortin I was found in the Triton-soluble fraction of both resting and thrombin-activated platelets and was not covalently bound to skeletal components. Without detergents, when resting platelets were lysed and fractionated in the absence of Ca2+, lipocortin I was found only in the cytosolic fraction, whereas, in the presence of Ca2+, lipocortin I was associated only with the crude particulate and not with the membrane nor the cytosolic fractions.

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