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. 1993 Jan;271(1):103-6.
doi: 10.1007/BF00297547.

Avian epidermis contains ATPase- and Ia-positive Langerhans-like cells

N Akhter  1 , M Kobayashi, T Hoshino
Affiliations

Avian epidermis contains ATPase- and Ia-positive Langerhans-like cells

N Akhter et al. Cell Tissue Res. 1993 Jan.

Abstract

The occurrence of cells resembling mammalian Langerhans cells in the avian epidermis was studied by ATPase histochemistry, Ia immunoreactivity and electron microscopy. The existence of MHC class II antigen-(Ia) expressing, ATPase-positive dendritic cells, which are ultrastructurally similar to mammalian Langerhans cells except for the absence of Birbeck granules, was demonstrated. These cells may be a basic component of the immune system of birds.

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