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Clinical Trial
. 1993 Feb;40(2):119-21.
doi: 10.1007/BF03011307.

Nasal ketamine for paediatric premedication

N Weksler  1 , L Ovadia, G Muati, A Stav
Affiliations
Clinical Trial

Nasal ketamine for paediatric premedication

N Weksler et al. Can J Anaesth. 1993 Feb.

Abstract

Ketamine in a dose of 6 mg.kg-1 was nasally administered in 86 healthy children (ASA I and II), aged from two to five years undergoing elective general, urological or plastic surgery, 20 to 40 min before the scheduled surgery time. These children were compared with 62 others, also aged from two to five years, in whom promethazine and meperidine, 1 mg.kg-1 of each, were injected im. Sedation was started as excellent in 48 and as adequate in 19 children in the ketamine group, compared with nine and 12 respectively in Group 2 (P < 0.05), while salivation was similar in both groups. We conclude that nasal ketamine is an alternative to im preanaesthetic sedation administration in children aged from two to five years.

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