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. 1993 Mar;6(2):73-6.
doi: 10.1007/BF00336648.

The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation

S Takaya  1 , T Nonami, R Selby, H Doyle, G Murray, D Kramer, Y Kang, T E Starzl
Affiliations

The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation

S Takaya et al. Transpl Int. 1993 Mar.

Abstract

The early postoperative hemodynamic data of 88 patients who underwent primary liver transplantation between July 1989 and October 1990 at the University Health Center of Pittsburgh were analyzed to establish the relationship of systemic hemodynamics and oxygen consumption to perioperative allograft function. The 15 patients whose allografts failed within the 1st month following transplantation were designated as group 1, while 73 patients who retained adequate graft function constituted group 2. Although the cardiac index and oxygen delivery did not differ significantly between the groups, group 1 consistently demonstrated a lower mean arterial pressure, oxygen consumption, arteriovenous oxygen content difference, and arterial ketone body ratio. The etiology of reduced oxygen consumption in group 1 patients is speculative, but the data support the notion that oxygen consumption is a useful, predictive indicator for liver allograft function after transplantation.

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Figures

Fig. 1
Fig. 1
Comparison of arteriovenous oxygen content difference (AVDO2) and oxygen consumption (V̇O2) between group 1 (□) and group 2 (■) patients. V̇O2 in group 1 was significantly lower than that in group 2 (P < 0.01), which was followed by smaller AVDO2 (P < 0.05)
Fig. 2
Fig. 2
Correlation of systemic oxygen consumption (V̇O2) and arterial ketone body ratio (AKBR). V̇O2 showed a significant correlation with the same day’s AKBR values after primary liver transplantation (r = 0.66, P < 0.001)
See this image and copyright information in PMC

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