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Review
. 1993 Feb;5(1):82-7.
doi: 10.1016/s0955-0674(05)80012-2.

Dystrophin and the membrane skeleton

Affiliations
Review

Dystrophin and the membrane skeleton

J M Ervasti et al. Curr Opin Cell Biol. 1993 Feb.

Abstract

Recent studies have confirmed several predictions concerning the structure and possible function of dystrophin, including a direct interaction with F-actin and an indirect interaction with laminin via linkage through a transmembrane protein complex. The results of the past year support a role for dystrophin in linking the actin cytoskeleton with the extracellular matrix in striated muscle, but they have not explained its function in other tissues.

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