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Case Reports
. 1993 Mar;32(3):254-6.
doi: 10.1093/rheumatology/32.3.254.

Polyautoimmunity in a young woman

N J Sheehan  1 , K Stanton-King
Affiliations
Case Reports

Polyautoimmunity in a young woman

N J Sheehan et al. Br J Rheumatol. 1993 Mar.

Abstract

A young woman with the HLA phenotype A1, A2, B5, B8, DR3, DR4 developed RA, idiopathic thrombocytopenic purpura (ITP), pernicious anaemia (PA), Hashimoto's thyroiditis (HT), systemic sclerosis (SS), pancreatic exocrine insufficiency (PEI) and coeliac disease (CD) before dying from vasculitic complications. A family study revealed RA, PA and insulin-dependent diabetes mellitus (IDDM) amongst her first degree relatives. Her case emphasizes the clinical and immunogenetic links between the autoimmune diseases.

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