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Review
. 1993 Feb;3(1):44-9.
doi: 10.1016/s0959-437x(05)80339-9.

The role of c-myc in cell growth

G I Evan  1 , T D Littlewood
Affiliations
Review

The role of c-myc in cell growth

G I Evan et al. Curr Opin Genet Dev. 1993 Feb.

Abstract

Recent experiments have established that the c-myc oncogene encodes a sequence-specific DNA-binding protein that interacts with a specific intracellular partner, Max, and probably manifests its effects through transcriptional modulation. In addition, the range of biological functions attributed to expression of c-myc has grown to include not only transformation and mitogenesis but also cell death.

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