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. 1977 Apr;31(3):369-78.
doi: 10.1016/0022-510x(77)90215-5.

Correlation of single fibre EMG and muscle histochrmistry using an open biopsy recording technique

Correlation of single fibre EMG and muscle histochrmistry using an open biopsy recording technique

M S Schwartz et al. J Neurol Sci. 1977 Apr.

Abstract

Single fibre electromyographic (SFEMG) recordings were carried out during open muscle biopsy. Nine patients were studied, including 5 with Duchenne muscular dystrophy, 2 with spinal muscular atrophy and 1 each with limb-girdle dystrophy and myotonic dystrophy. Correlations were possible between the SFEMG fibre density determinations and histochemical evidence of grouping in some biopsies, particularly involving Type I fibres. This combined technique permits an improved assessment of the functional state of abnormal muscle.

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