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. 1993 Apr;52(4):767-76.

Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21

S A Smith  1 , D F Easton, D Ford, J Peto, K Anderson, D Averill, M Stratton, M Ponder, C Pye, B A Ponder
Affiliations

Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21

S A Smith et al. Am J Hum Genet. 1993 Apr.

Abstract

In a study of 31 breast cancer families and 12 breast-ovarian cancer families, we have obtained clear evidence of linkage to markers on chromosome 17q in the families with ovarian cancer (maximum lod score 3.34 at theta = .04) but only weak evidence in those without ovarian cancer. Recombinant events indicate that the gene lies between D17S588 and D17S250.

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References

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