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Comparative Study
. 1993 Apr;16(4):578-80.
doi: 10.2337/diacare.16.4.578.

Exaggerated hyperglycemia after a pizza meal in well-controlled diabetes

J A Ahern  1 , P M Gatcomb, N A Held, W A Petit Jr, W V Tamborlane
Affiliations
Comparative Study

Exaggerated hyperglycemia after a pizza meal in well-controlled diabetes

J A Ahern et al. Diabetes Care. 1993 Apr.

Abstract

Objective: To examine whether the postprandial hyperglycemic effect of pizza in well-controlled IDDM patients is related to overeating or to unique properties of this popular food.

Research design and methods: On two evenings, each patient (n = 8) consumed a meal that was similar in macronutrient composition except that one consisted of pizza and the other was a control meal that included high glycemic index foods. The insulin regimen was held constant.

Results: Postprandial glucose levels were within the target range (< or = 10 mM) after the control meal. Although the initial glucose increase was similar for the two meals, plasma glucose continued to rise and was significantly increased from 4 to 9 h after ingestion of pizza compared with the control meal (P < 0.05). This increase occurred even though free insulin, glucagon, and free fatty acid levels did not differ significantly.

Conclusions: Our data suggest that pizza has properties that accentuate and sustain postprandial hyperglycemia.

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Comment in

  • An unsuspected factor contributing to pizza hyperglycemia.
    Tatti P, Di Mauro P, Guarisco R. Tatti P, et al. Diabetes Care. 1993 Oct;16(10):1409-10. doi: 10.2337/diacare.16.10.1409. Diabetes Care. 1993. PMID: 8269806 No abstract available.
  • The pizza saga.
    Wolever T. Wolever T. Diabetes Care. 1993 Oct;16(10):1410-1. doi: 10.2337/diacare.16.10.1410. Diabetes Care. 1993. PMID: 8269807 No abstract available.

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