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. 1993 Jan;99(1):37-41.
doi: 10.1007/BF00268018.

Carbonic anhydrase isoenzymes II and I are present in the zona glomerulosa cells of the human adrenal gland

A K Parkkila  1 , S Parkkila, T Juvonen, H Rajaniemi
Affiliations

Carbonic anhydrase isoenzymes II and I are present in the zona glomerulosa cells of the human adrenal gland

A K Parkkila et al. Histochemistry. 1993 Jan.

Abstract

Human carbonic anhydrase isoenzymes I and II (HCA I and II) were purified from human erythrocytes by inhibitor affinity chromatography and ion-exchange chromatography. These isoenzymes were then located in the human adrenal gland using specific polyclonal antisera raised in rabbits and specific detection by immunohistochemical techniques. Both HCA II and I were located in the zona glomerulosa cells, although the staining for HCA I was faint. The cells of the zona fasciculata and the zona reticularis failed to stain with either antiserum. Control stainings with preimmune or anti-HCA VI sera were negative. The presence of HCA II and I in the zona glomerulosa cells may be linked to regulation of the biosynthesis or secretion of mineralocorticoids.

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References

    1. Ann N Y Acad Sci. 1984;429:516-24 - PubMed
    1. FEBS Lett. 1979 Sep 15;105(2):299-302 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Histochem Cytochem. 1990 Jul;38(7):941-7 - PubMed
    1. J Biol Chem. 1987 Jan 25;262(3):1382-8 - PubMed

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