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. 1993 Apr;175(8):2448-50.
doi: 10.1128/jb.175.8.2448-2450.1993.

Expression of gonococcal transferrin-binding protein 1 causes Escherichia coli to bind human transferrin

C N Cornelissen  1 , G D Biswas, P F Sparling
Affiliations

Expression of gonococcal transferrin-binding protein 1 causes Escherichia coli to bind human transferrin

C N Cornelissen et al. J Bacteriol. 1993 Apr.

Abstract

The gene for gonococcal transferrin-binding protein 1 (TBP1) was cloned behind an inducible promoter in Escherichia coli. The resultant strain was capable of binding human transferrin with the same specificity as that of the gonococcus. E. coli expressing TBP1 did not internalize transferrin-bound iron or grow on transferrin as a sole iron source.

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