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Review
. 1993;14(3):176-82.
doi: 10.1002/micr.1920140308.

Pharmacologic intervention in ischemia-induced reperfusion injury in the skeletal muscle

C Y Pang  1 , C R Forrest, R Mounsey
Affiliations
Review

Pharmacologic intervention in ischemia-induced reperfusion injury in the skeletal muscle

C Y Pang et al. Microsurgery. 1993.

Abstract

This article provides a concise review on the potential causes of ischemia-induced reperfusion (I/R) injury and pharmacologic intervention in the skeletal muscle. Special emphasis is placed on the recent observation of the acute ischemic preconditioning phenomenon for prevention of I/R injury in skeletal muscle. Finally, the mechanism of ischemic preconditioning and its clinical applications for augmentation of skeletal muscle tolerance to prolonged ischemic insult are discussed.

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