Review
doi: 10.1159/000236429.
Pathogenic significance and diagnostic value of lupus autoantibodies
Affiliations
- PMID: 8481649
- DOI: 10.1159/000236429
Item in Clipboard
Review
Pathogenic significance and diagnostic value of lupus autoantibodies
Int Arch Allergy Immunol.
1993.
Abstract
Systemic lupus erythematosus (SLE) is characterized by a panoply of autoantibodies (more than 50). Some of them are more prevalent (anti-ds DNA > 80%) while others are less frequently detected, but highly specific for SLE (anti-Sm, 20%). In this review we will discuss the clinical significance of anti-RNP, anti-Ro, anti-La and anti-phospholipid antibodies. We will also summarize the clinical and experimental evidence for the pathogenic role attributed to each one of these antibodies.
Similar articles
-
Autoantibodies.Rheum Dis Clin North Am. 1988 Apr;14(1):43-56. Rheum Dis Clin North Am. 1988. PMID: 2969602 Review.
-
Autoantibodies to ribonucleoproteins.Clin Rheum Dis. 1985 Dec;11(3):485-505. Clin Rheum Dis. 1985. PMID: 2934209 Review.
-
Antinuclear antibodies in systemic lupus erythematosus.Med J Malaysia. 1989 Jun;44(2):151-5. Med J Malaysia. 1989. PMID: 2626124
-
Systemic lupus erythematosus. Antibodies to ribonuclear proteins.Rheum Dis Clin North Am. 1994 Feb;20(1):29-43. Rheum Dis Clin North Am. 1994. PMID: 8153403 Review.
-
Idiotypic independency of anti-dsDNA and anti-Sm antibodies in SLE sera.Clin Exp Rheumatol. 1989 Sep-Oct;7(5):572-3. Clin Exp Rheumatol. 1989. PMID: 2591135 No abstract available.
Cited by
-
Canine antinuclear antibodies: comparison of immunofluorescence staining patterns and precipitin reactivity.Acta Vet Scand. 1999;40(3):205-12. doi: 10.1186/BF03547018. Acta Vet Scand. 1999. PMID: 10605137 Free PMC article.
-
Successful treatment of DEAP-HUS with eculizumab.Pediatr Nephrol. 2014 May;29(5):841-51. doi: 10.1007/s00467-013-2654-x. Epub 2013 Nov 20. Pediatr Nephrol. 2014. PMID: 24249282
-
Anti-human immunodeficiency virus type 1 antibodies of noninfected subjects are not related to autoantibodies occurring in systemic diseases.Clin Diagn Lab Immunol. 1995 Jul;2(4):458-61. doi: 10.1128/cdli.2.4.458-461.1995. Clin Diagn Lab Immunol. 1995. PMID: 7583924 Free PMC article.
-
The role of B cells in lupus pathogenesis.Int J Biochem Cell Biol. 2010 Apr;42(4):543-50. doi: 10.1016/j.biocel.2009.10.011. Epub 2009 Oct 20. Int J Biochem Cell Biol. 2010. PMID: 19850148 Free PMC article. Review.
-
Anticardiolipin antibodies are elevated in drug-free, multiply affected families with schizophrenia.J Clin Immunol. 1994 Jan;14(1):73-8. doi: 10.1007/BF01541177. J Clin Immunol. 1994. PMID: 8132739
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
