Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Mar;29(2):136-41.

Mental retardation associated with "balanced" chromosome rearrangements

S J Funderburk, M A Spence, R S Sparkes

Mental retardation associated with "balanced" chromosome rearrangements

S J Funderburk et al. Am J Hum Genet. 1977 Mar.

Abstract

Balanced chromosome rearrangements were found in seven of 455 retarded children vs. four of 1,679 nonretarded, psychiatric children (P less than .05). The combined incidence of non-Robertsonian balanced rearrangements from this and reported surveys of the mentally retarded was five times greater than that from newborn surveys, whereas Robertsonian translocations were not increased among the retarded. The combined data show an increase in de novo rather than familial rearrangements among the retarded; the increase in de novo rearrangements is specifically for non-Robertsonian translocation.

PubMed Disclaimer

References

    1. Am J Dis Child. 1972 Jun;123(6):561-4 - PubMed
    1. Lancet. 1971 Oct 30;2(7731):971-2 - PubMed
    1. J Med Genet. 1974 Mar;11(1):50-64 - PubMed
    1. Chromosoma. 1970;30(2):215-27 - PubMed
    1. Nord Med. 1970 Apr 16;83(16):498-500 - PubMed

Publication types

LinkOut - more resources