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. 1993 Feb;6(2):71-3.

[Disodium pamidronate (APD) in the treatment of bone metastases]

[Article in Portuguese]
L Costa  1 , C Moreira, E B da Costa
Affiliations
  • PMID: 8488764
Free article

[Disodium pamidronate (APD) in the treatment of bone metastases]

[Article in Portuguese]
L Costa et al. Acta Med Port. 1993 Feb.
Free article

Abstract

Diphosphonates are potent inhibitors of bone resorption, they have been evaluated in several clinical trials for bone metastases. We performed a clinical study to evaluate the therapeutic effect of Disodium Pamidronate over pain and radiologic evolution in bone metastases (Breast Cancer and Multiple Myeloma patients). The results regarding the first 10 patients concluded that there is good drug tolerability and significant analgesic activity in 6 patients, with sclerosis of lytic skull lesions in one breast cancer patient.

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