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. 1977 Feb;11(2):277-80.
doi: 10.1128/AAC.11.2.277.

Amphotericin B susceptibility testing of yeasts with a bactec radiometric system

R L Hopfer, D Gröschel

Amphotericin B susceptibility testing of yeasts with a bactec radiometric system

R L Hopfer et al. Antimicrob Agents Chemother. 1977 Feb.

Abstract

The effect of amphotericin B on CO(2) production was studied using a Bactec 225. A radiometric procedure for yeast susceptibility testing that requires 3 h of incubation was developed. A total of 48 yeast isolates was tested in this system and the results were correlated to tube dilution studies. The drug concentration causing at least a 44% decrease in CO(2) production correlated to the tube dilution minimal inhibitory concentration in 85% of isolates tested and was within one tube dilution of the minimal inhibitory concentration in over 95% of yeasts tested.

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References

    1. Antimicrob Agents Chemother. 1974 Jul;6(1):29-33 - PubMed
    1. Antimicrob Agents Chemother. 1972 Nov;2(5):405-12 - PubMed
    1. Antimicrob Agents Chemother. 1972 Nov;2(5):360-66 - PubMed

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