Giant melanosomes in multiple lentigines syndrome
- PMID: 848980
Giant melanosomes in multiple lentigines syndrome
Abstract
Biopsy specimens of normal skin and lentigines from an 82-year-old man with multiple lentigines syndrome were examined with light and electron microscopes. Giant melanosomes were found in dermal melanophages, melanocytes, and keratinocytes in all epidermal layers. Morphologic characteristics of these melanosomes are described, and other conditions in which they have been found are discussed.
Similar articles
-
Multiple lentigines syndrome: a comparison of normal skin and lentiginous skin by electron microscopy and immunohistochemical staining.J Dermatol. 1998 Jun;25(6):400-5. doi: 10.1111/j.1346-8138.1998.tb02422.x. J Dermatol. 1998. PMID: 9675349
-
Ultrastructure of giant pigment granules in lentigo simplex.Acta Derm Venereol. 1978;58(3):223-9. Acta Derm Venereol. 1978. PMID: 78636
-
Giant and "granular melanosomes" in Leopard syndrome: an ultrastructural study.J Cutan Pathol. 1976;3(5):207-16. doi: 10.1111/j.1600-0560.1976.tb00865.x. J Cutan Pathol. 1976. PMID: 1018060
-
Sun-induced freckling: ephelides and solar lentigines.Pigment Cell Melanoma Res. 2014 May;27(3):339-50. doi: 10.1111/pcmr.12232. Epub 2014 Mar 3. Pigment Cell Melanoma Res. 2014. PMID: 24517859 Review.
-
Segmental lentiginosis with "jentigo" histologic pattern.Am J Dermatopathol. 1992 Aug;14(4):323-7. Am J Dermatopathol. 1992. PMID: 1503204 Review.
Cited by
-
The ultrastructure of conjunctival melanocytic tumors.Trans Am Ophthalmol Soc. 1984;82:599-752. Trans Am Ophthalmol Soc. 1984. PMID: 6398936 Free PMC article. Review.
-
Zinc deficiency leads to lipofuscin accumulation in the retinal pigment epithelium of pigmented rats.PLoS One. 2011;6(12):e29245. doi: 10.1371/journal.pone.0029245. Epub 2011 Dec 22. PLoS One. 2011. PMID: 22216222 Free PMC article.
-
Premature cataracts associated with generalized lentigo.Trans Am Ophthalmol Soc. 1979;77:121-32. Trans Am Ophthalmol Soc. 1979. PMID: 545823 Free PMC article.
-
Multiple lentigines syndrome (LEOPARD syndrome or progressive cardiomyopathic lentiginosis).J Med Genet. 1997 Jul;34(7):582-6. doi: 10.1136/jmg.34.7.582. J Med Genet. 1997. PMID: 9222968 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources