The release of alanine by rat diaphragm muscle in vitro
- PMID: 849291
- PMCID: PMC1164613
- DOI: 10.1042/bj1620399
The release of alanine by rat diaphragm muscle in vitro
Abstract
Alanine release by rat diaphragm muscle in vitro is stimulated by glutamate, valine, leucine and glucose. The stimulation by glutamate and valine (but not leucine) is inhibited by 3-mercaptopicolinate. These results suggest a metabolic route involving phosphoenolpyruvate carboxykinase which directs amino acid carbon skeletons towards pyruvate synthesis for alanine formation.
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