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. 1977 Feb 15;162(2):399-403.
doi: 10.1042/bj1620399.

The release of alanine by rat diaphragm muscle in vitro

The release of alanine by rat diaphragm muscle in vitro

K Snell et al. Biochem J. .

Abstract

Alanine release by rat diaphragm muscle in vitro is stimulated by glutamate, valine, leucine and glucose. The stimulation by glutamate and valine (but not leucine) is inhibited by 3-mercaptopicolinate. These results suggest a metabolic route involving phosphoenolpyruvate carboxykinase which directs amino acid carbon skeletons towards pyruvate synthesis for alanine formation.

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