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. 1993 Apr;37(4):741-5.
doi: 10.1128/AAC.37.4.741.

In vitro antimicrobial activity of a new antibiotic, MDL 62,879 (GE2270 A)

B P Goldstein  1 , M Berti, F Ripamonti, A Resconi, R Scotti, M Denaro
Affiliations

In vitro antimicrobial activity of a new antibiotic, MDL 62,879 (GE2270 A)

B P Goldstein et al. Antimicrob Agents Chemother. 1993 Apr.

Abstract

MDL 62,879 (GE2270 A) is a new peptide antibiotic that inhibits protein synthesis through an interaction with elongation factor Tu. MDL 62,879 was very active against gram-positive clinical isolates, particularly staphylococci and enterococci, for which MICs for 90% of isolates were < or = 0.13 micrograms/ml. It was equally active against isolates resistant to beta-lactams, erythromycin, gentamicin, and glycopeptides. It also had activity against Mycobacterium tuberculosis. MDL 62,879 had moderate bactericidal activity against staphylococci.

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