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Case Reports
. 1977 Jan;27(1):23-9.

A second case of human C3b inhibitor (KAF) deficiency

R A Thompson, P J Lachmann
Case Reports

A second case of human C3b inhibitor (KAF) deficiency

R A Thompson et al. Clin Exp Immunol. 1977 Jan.

Abstract

The second case of C3b inhibitor deficiency is described in an 11-year-old girl who presented with recurrent attacks of meningitis, in between which she was well. Her serum showed all of the complement component changes noted in the first described case, although showing only a relatively slight defect in its ability to opsonize bacteria for phagocytosis and killing by polymorphonuclear leucocytes. This correlated with the patient's freedom from other infections.

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References

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    1. Lancet. 1972 Dec 2;2(7788):1179-81 - PubMed
    1. Br Med J. 1974 Jul 6;3(5922):16-8 - PubMed
    1. J Immunol. 1972 Mar;108(3):837-40 - PubMed
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