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. 1993 Mar;132(2):137-45.
doi: 10.1007/BF00239003.

Carrier-mediated residual K+ and Na+ transport of human red blood cells

K Denner  1 , R Heinrich, I Bernhardt
Affiliations

Carrier-mediated residual K+ and Na+ transport of human red blood cells

K Denner et al. J Membr Biol. 1993 Mar.

Abstract

Residual, i.e., (ouabain, bumetanide, and EGTA)-insensitive K+ and Na+ influxes as well as effluxes of human red blood cells are enhanced in isotonic solutions of low (NaCl + KCl) concentration using sucrose to maintain constant osmolarity. Various carrier models were tested to fit the experimental data of these fluxes simultaneously. The residual K+ and Na+ fluxes can be described on the basis of a carrier mechanism of competing substrates with modifier sites.

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