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Case Reports
. 1993 Feb;69(808):153-4.
doi: 10.1136/pgmj.69.808.153.

Solitary plasmacytoma of bone--a rare disorder with an unusual evolution

R K Ganjoo  1 , J S Malpas, P N Plowman
Affiliations
Case Reports

Solitary plasmacytoma of bone--a rare disorder with an unusual evolution

R K Ganjoo et al. Postgrad Med J. 1993 Feb.

Abstract

A 40 year old woman presented with a spinal epidural tumour, which on histology was shown to be a plasmacytoma. At that time she had no evidence of multiple myeloma. Ten months later, she developed a second isolated plasmacytoma in the spleen, for which she underwent splenectomy. Two years after her initial presentation she had another recurrence in the liver, followed by a full-blown picture of multiple myeloma. The myeloma was progressive and resistant to all forms of chemotherapy. She finally died of a massive gastrointestinal haemorrhage. The clinical features, natural evolution and management of solitary plasmacytomas are discussed.

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