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Review
. 1993 Apr;5(2):263-7.
doi: 10.1016/0952-7915(93)90015-k.

Production of human antibodies using bacteriophage

A D Griffiths  1
Affiliations
Review

Production of human antibodies using bacteriophage

A D Griffiths. Curr Opin Immunol. 1993 Apr.

Abstract

The immune system produces antibodies by a process of antigen-driven selection. An in vitro process of antigen-driven selection, based on the display of antibody fragments on filamentous bacteriophage, has recently been developed. This enables human antibody fragments of high affinity and specificity to be produced without immunization.

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