A comparison of topical non-steroidal anti-inflammatory drugs to steroids for control of post cataract inflammation
- PMID: 8509683
A comparison of topical non-steroidal anti-inflammatory drugs to steroids for control of post cataract inflammation
Abstract
Fifty patients undergoing phacoemulsification with posterior chamber intraocular lens implantation were randomly assigned to receive either diclofenac sodium 0.1% eye drops (Voltaren Ophthalmic, CibaVision Ophthalmics, Duluth, GA) or prednisolone acetate 1.0% eye drops (Pred Forte, Allergan Pharmaceuticals, Irvine, CA) as their postoperative anti-inflammatory medication. The patients were examined one day, one week, and one month after surgery, and their postoperative inflammation was evaluated both by slit lamp assessment of cell and flare, and by objective measurement of cell and flare with the Kowa FC-1000 laser cell and flare meter. At each visit, the level of postoperative inflammation was the same for the two study groups. Thus diclofenac sodium was as effective an anti-inflammatory agent for postoperative inflammation as prednisolone acetate.
Similar articles
-
Clinical trial of diclofenac sodium (Naclof) eye drops on Nigerians.Niger Postgrad Med J. 2004 Dec;11(4):265-8. Niger Postgrad Med J. 2004. PMID: 15627154 Clinical Trial.
-
A randomized double-masked trial comparing ketorolac tromethamine 0.5%, diclofenac sodium 0.1%, and prednisolone acetate 1% in reducing post-phacoemulsification flare and cells.Ophthalmic Surg Lasers. 1998 Jul;29(7):539-44. Ophthalmic Surg Lasers. 1998. PMID: 9674003 Clinical Trial.
-
A comparison of topical diclofenac with prednisolone for postcataract inflammation.Arch Ophthalmol. 1995 Jun;113(6):725-7. doi: 10.1001/archopht.1995.01100060051031. Arch Ophthalmol. 1995. PMID: 7786212 Clinical Trial.
-
Preoperative and postoperative use of nonsteroidal antiinflammatory drugs in cataract surgery.Insight. 1996 Apr;21(1):13-6. doi: 10.1016/s1060-135x(96)90025-1. Insight. 1996. PMID: 8826226 Review.
-
Difluprednate versus Prednisolone Acetate after Cataract Surgery: a Systematic Review and Meta-Analysis.BMJ Open. 2019 Nov 2;9(11):e026752. doi: 10.1136/bmjopen-2018-026752. BMJ Open. 2019. PMID: 31678934 Free PMC article.
Cited by
-
The emerging roles of topical non-steroidal anti-inflammatory agents in ophthalmology.Br J Ophthalmol. 1996 May;80(5):480-5. doi: 10.1136/bjo.80.5.480. Br J Ophthalmol. 1996. PMID: 8695573 Free PMC article. Review. No abstract available.
-
Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives.Drug Deliv Transl Res. 2021 Jun;11(3):866-893. doi: 10.1007/s13346-020-00843-z. Drug Deliv Transl Res. 2021. PMID: 32901367 Review.
-
Comparison of prednisolone 1%, rimexolone 1% and ketorolac tromethamine 0.5% after cataract extraction: a prospective, randomized, double-masked study.Graefes Arch Clin Exp Ophthalmol. 2005 Aug;243(8):768-73. doi: 10.1007/s00417-005-1126-9. Epub 2005 Mar 9. Graefes Arch Clin Exp Ophthalmol. 2005. PMID: 15756571 Clinical Trial.
-
Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery.Cochrane Database Syst Rev. 2017 Jul 3;7(7):CD010516. doi: 10.1002/14651858.CD010516.pub2. Cochrane Database Syst Rev. 2017. PMID: 28670710 Free PMC article.
-
Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery.Korean J Ophthalmol. 2021 Jun;35(3):188-197. doi: 10.3341/kjo.2020.0135. Epub 2021 Jun 4. Korean J Ophthalmol. 2021. PMID: 34120417 Free PMC article. Clinical Trial.