Failure of poxvirus replication in the presence of an inhibitor of nucleolar RNA synthesis
- PMID: 851397
- DOI: 10.1007/BF01314857
Failure of poxvirus replication in the presence of an inhibitor of nucleolar RNA synthesis
Abstract
In vaccinia virus infected cells the appearance of a late enzyme RNA polymerase was prevented by MPB, an inhibitor of nucleolar RNA synthesis, although inductions of the early enzymes thymidine kinase and DNA polymerase were not affected. It is inferred the nucleoli may be involved in the replication of vaccinia virus.