Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jan 1;161(1):189-92.
doi: 10.1042/bj1610189.

Partial amino acid sequence of rat pre-prolactin

R A Maurer, J Gorski, D J McKean

Partial amino acid sequence of rat pre-prolactin

R A Maurer et al. Biochem J. .

Abstract

Rat pituitary mRNA was used to direct the cell-free synthesis of pre-prolactin labelled with [4,5-3H]leucine and either [35S] methioninc or [35S] cystine. Sequence analysis of the labelled protein indicates that pre-prolactin has 29 amino acid residues joined to the N-terminus of the prolactin sequence. Leucine residues were found at positions 13, 14, 15, 16, 21 and 22, methionine residues at positions 1, 17 and 18, and a cysteine residue at position 24 of the precursor sequence, and this partial sequence shows considerable similarity with other precursors that have been sequenced.

PubMed Disclaimer

References

    1. Biochemistry. 1972 May 23;11(11):2014-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1972 Jul;69(7):1967-71 - PubMed
    1. Proc Natl Acad Sci U S A. 1974 Sep;71(9):3731-5 - PubMed
    1. Biochemistry. 1974 Jul 16;13(15):3048-51 - PubMed
    1. J Cell Biol. 1975 Dec;67(3):835-51 - PubMed